Fifth Disease: Symptoms, Causes & Treatment Info

Fifth Disease: Symptoms, Causes & Treatment Info

Fifth Disease, or slapped cheek syndrome, is a common childhood viral infection; understand the symptoms like the distinctive rash, potential health conditions, plus treatment and prevention tips.


Have you noticed those rosy cheeks on kids and, um, a light rash? Could be Fifth Disease! What is it, though? We’re going to unpack all the essential info about Fifth Disease – also known as slapped cheek syndrome. Let’s get to it!

What Is Fifth Disease?

Fifth disease is a viral illness caused by the parvovirus B19. It ranks fifth in the historical classification of common childhood rash illnesses, hence, the name. Think back to elementary school–it was always something making the rounds, wasn’t it? I recall distinctly, there was that one kid that always had something.

It’s one of the widespread childhood infections, which is why approximately 50% of adults are immune. Though, we should still go over some of the symptoms!

Quick Facts You Should Know About Fifth Disease:

  • It’s considered a viral disease.
  • Common symptoms: fever, fatigue, headache, redness and rash on the cheeks, joint pain, and a general skin rash.
  • Fifth disease can lead to health complications in rare cases.
  • It can cause fetal complications during pregnancy.
  • The patient may become non-contagious once the skin rash appears.

Fifth Disease Symptoms

Let’s explore the various symptoms associated with Fifth Disease:

1. Common Fifth Disease Symptoms

The early signs often resemble those of the flu. Pretty standard stuff, but, they can include:

  • Headache.
  • Fatigue.
  • Mild fever.
  • Sore throat.
  • Nausea.
  • Runny nose.
  • Nasal congestion.

Symptoms typically appear around 4-14 days after exposure to the virus. Several days after the initial symptoms, patients usually develop a distinctive red rash on their cheeks, giving the appearance of “slapped cheeks.”

The rash often spreads to the arms, legs, and body, lasting for several days. Sometimes, this rash looks like a lacy pattern. When you feel a bit under the weather, or notice a rash, you may not be contagious.

2. Uncommon Fifth Disease Symptoms

About 5% of children and half of adults who contract the disease experience joint pain. This type of joint inflammation is more prevalent among adults, especially women, and can last from days to weeks.

In addition, people with joint inflammation, due to fifth disease, may experience a tingling sensation in their fingers, along with redness, and warmth in the joints across their body. It is said that the joints most often affected are the wrists, fingers, and knees.

Before we dive deeper into other topics, a relevant question: What steps can you take to support your immune system during this time? Many people add elderberry supplements or increase vitamin C intake. These, along with rest, can help your body’s defense mechanisms do what they do best.

In some cases, Fifth Disease can lead to complications such as Erythrocyte aplasia, where bone marrow temporarily stops producing red blood cells. This condition can be life-threatening.

Individuals with underlying immune deficiencies are more susceptible to these complications.
That said, pregnant women who contract Fifth Disease for the first time should avoid contact with infected individuals because the virus can pass to the fetus and cause anemia or even miscarriage.

Fifth Disease Treatment

There is no specific treatment for Fifth Disease, but symptom management and certain medications can alleviate discomfort. However, the use of live vaccines isn’t advised in this case.

If someone with underlying joint inflammation contracts Fifth Disease, a doctor may prescribe medication to address the inflammation.

For children, rest is often enough. If the child experiences itching, a doctor may prescribe specific creams and medications.

Prevention Tips for Fifth Disease

Like most common illnesses, the best ways to prevent infection are:

  • Wash your hands frequently and thoroughly.
  • Cover your mouth and nose when coughing or sneezing.
  • Stay home when sick.

Key takeaways

  • Fifth disease is a viral illness, often mild, that’s caused by parvovirus B19.
  • It’s characterized by flu-like symptoms and a distinctive “slapped cheek” rash.
  • While usually harmless, it can pose risks to pregnant women and individuals with compromised immune systems.

FAQ, Myth & Facts

Is Fifth Disease dangerous?

For most healthy children and adults, Fifth Disease is mild and resolves on its own. However, it can be more serious for pregnant women, individuals with weakened immune systems, or those with certain blood disorders.

Is there a vaccine for Fifth Disease?

No, there is currently no vaccine available for Fifth Disease.

How long is someone contagious with Fifth Disease?

People are typically contagious before the rash appears. Once the rash is visible, they are generally no longer contagious.

Myth: Fifth Disease is always a serious illness.

Fact: In most cases, Fifth Disease is a mild, self-limiting illness, especially in children.

Myth: Only children can get Fifth Disease.

Fact: While it’s more common in children, adults can also contract Fifth Disease.

My kiddo caught it last year. The rash was pretty alarming at first, but honestly, it cleared up within a week with just rest and some Tylenol. I was more worried than she was! Glad it’s all behind us!

As a teacher, I’ve seen it all. Fifth Disease is definitely one of those things that goes around the classroom. We just keep emphasizing hand washing and try to keep things as clean as possible. Thankfully, it’s usually not too bad.

I remember getting it when I was pregnant with my second. It was super scary because of all the stuff you read online. My doctor kept a close eye on everything, and thankfully, everything turned out fine. But, yeah, it was a stressful time.

So, there you have it: a rundown of Fifth Disease. While it might sound a little scary, remember that it’s generally a mild illness, especially in kids. Of course, if you’re at all concerned, always check in with your doctor. We’ve explored what this illness is, its symptoms, and some things you should know about it. It’s always good to be informed, right? Personally, I learned a lot while writing this; I didn’t realize how common it was!

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